Modeling of chromosomal epigenetic silencing processes

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Abstract

Silenced genes in eukaryotes are packaged into heterochromatin. In addition to establishing a passive storage site for inactive genes in differentiated cells, silencing can play an active role in promoting cellular differentiation. Here, we describe quantitative modeling of silencing processes. © 2011 Landes Bioscience.

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Becskei, A., Scherrer, S., Kelemen, J. Z., & Murray, A. E. (2011). Modeling of chromosomal epigenetic silencing processes. Transcription, 2(4), 173–178. https://doi.org/10.4161/trns.2.4.16344

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