Abstract
Alzheimer's disease (AD) is characterized by the pathological accumulation of amyloid β (Aβ) plaques and neurofibrillary tangles composed of hyperphosphorylated tau. Microglia and astrocytes respond to the abnormal presence of tau protein with induced transposable element (TE) transcription. In this Forum, we discuss new data that link dysregulated TE expression to AD pathogenesis.
Author supplied keywords
Cite
CITATION STYLE
APA
Evering, T. H., Marston, J. L., Gan, L., & Nixon, D. F. (2023, March 1). Transposable elements and Alzheimer’s disease pathogenesis. Trends in Neurosciences. Elsevier Ltd. https://doi.org/10.1016/j.tins.2022.12.003
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
Already have an account? Sign in
Sign up for free