Bacteriophage: A Potential Therapeutic Agent (A Review)

Abstract

A review. Scientists all over the world are trying to develop new antibiotics against bacteria to overcome the threat of "superbugs" (antibiotic-resistant bacteria). In this context, bacteriophage might be possible alternative weapon. Bacteriophage could use clin. as therapeutic agent for various human infectious complications e.g. surgical wound infections, post burn infections, eye infections, cerebrospinal meningitis etc. and also in many animal disease treatment such as Klebsiella infection in white mice, sepsis, pneumonia, colonization of the gastrointestinal tract with Vancomycin-Resistant Enterococcus faecium (VRE) in bacteremic mice model etc. Bacteriophage has many other applications and as bactericidal agent in food industries. It also holds a great potential in vaccine development as well as in cancer and HIV research. In this study, identifying the problems of therapeutic applications we discussed their possible solutions Also detecting, future possible implications of bacteriophage and making comparison with antibiotics and chemotherapeutics, we found it advantageous as a potential therapeutic agent.