Seroepidemiology of hepatitis E virus infection in 2-25-year-olds in Sari district, Islamic Republic of Iran

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Abstract

The seroprevalence of hepatitis E virus infection (HEV) in children and young adults was determined in a community-based survey in an area of northern Islamic Republic of Iran. Serum samples were taken from 1080 randomly selected apparently healthy 2-25-year-olds from urban and rural regions of Sari district. Anti-HEV IgG antibodies were detected in 25 individuals (2.3%). Seroprevalence increased significantly with age from 3/255 (1.2%) in children < 10 years to 8/110 (7.3%) in those aged 20-25 years. No differences in HEV status were noted between the sexes. Earlier age at exposure to infection and a higher infection rate were found in people residing in rural areas than in urban areas.

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Saffar, M. J., Farhadi, R., Ajami, A., Khalilian, A. R., Babamahmodi, F., & Saffar, H. (2009). Seroepidemiology of hepatitis E virus infection in 2-25-year-olds in Sari district, Islamic Republic of Iran. Eastern Mediterranean Health Journal, 15(1), 136–142. https://doi.org/10.26719/2009.15.1.136

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