Genome microbiology for synthetic applications

Abstract

Synthetic biology integrates the knowledge of engineering, mathematics and physics into the biological systems to investigate and get deeper insight into the natural cellular phenomena and thus is implicated for a variety of applications. A key step in synthetic biology is logical combination of simple circuits into higher-order systems which work like a genetic switchboard which is subsequently implicated in building novel biological entities on an ever more complex level for novel application. In recent years, the field has emerged extensively and constructed many complex circuits which find its use in several fields ranging from simple laboratory experiments to clinic. Most important application of synthetic biology is the development of novel and efficient therapies for the treatment of a large number of lifethreatening infectious diseases, development of vaccine, cell therapy, regenerative medicine and microbiome engineering. This chapter is aimed at providing a brief description on different applications of synthetic biology.