In this study, 6-[(4-arylidene-2-phenyl-5-oxoimidazolin-1-yl)phenyl]-4,5- dihydro-3(2H)-pyridazinone and 4-[(4-arylidene-2-phenyl-5-oxoimidazolin-1-yl) phenyl]-1(2H)-phthalazinone derivatives were synthesized by reacting 6-(4-aminophenyl)-4,5-dihydro-3(2H)-pyridazinone or 4-(4-aminophenyl)-1(2H)- phthalazinone compound with different 4-arylidene-2-phenyl-5(4H)-oxazolone derivatives. The vasodilator activities of the compounds were examined both in vitro and in vivo. Some pyridazinone derivatives showed appreciable activity.
CITATION STYLE
Demirayak, S., Karaburun, A. C., Kayagil, I., Erol, K., & Sirmagul, B. (2004). Some pyridazinone and phthalazinone derivatives and their vasodilator activities. Archives of Pharmacal Research, 27(1), 13–18. https://doi.org/10.1007/BF02980038
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