Red blood cell transfusion

Abstract

Transfusion is one of the most commonly performed procedures in hospitalized patients. General knowledge of blood product collection, manufacturing, storage, pretransfusion testing, and available red blood cell (RBC) modifications, allows the clinician to better communicate patient needs and understand what options may be available when ordering blood products. RBC transfusion offers benefits, but the clinician must comprehend the possibility of transfusion-related adverse events. Transfusing in the setting of hemorrhagic blood loss adds additional challenges regarding volume overload, coagulopathy, and optimum transfusion ratios. The information imparted in this chapter will help equip the clinician with the knowledge needed to make informed decisions for patients requiring RBC transfusion, especially injured patients.