Abstract
The aim of the present work is to study the potential of different Yeast Derived Nutrients (YDN) as supplements in mammalian cell culture serum-free media. Firstly, a screening of six yeast derived nutrients has been performed on the cell growth of a recombinant CHO cell line producing gamma-interferon, at small scale, in static cultures. The effects of YDN observed at this micro-scale have been validated in spinner flasks with regard to cell metabolism, gamma-interferon production and its glycosylation pattern.
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CITATION STYLE
Chevalot, I., Dziukala, C., Olmos, E., Marc, I., Druaux-Borreill, D., Oriol, E., & Marc, A. (2010). Use of Yeast Derived Nutrients for Cell Culture in Serum-Free Media. In Cells and Culture (pp. 843–846). Springer Netherlands. https://doi.org/10.1007/978-90-481-3419-9_148
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