Small Molecule Inhibitors of the PI3-Kinase Family

  • Knight Z
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Abstract

The PI3-K family is one of the most intensely pursued classes of drug targets. This chapter reviews some of the chemical and structural features that determine the selectivity of PI3-K inhibitors, by focusing on a few key compounds that have been instrumental in guiding our understanding of how to design drugs against this family.

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Knight, Z. A. (2010). Small Molecule Inhibitors of the PI3-Kinase Family (pp. 263–278). https://doi.org/10.1007/82_2010_44

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