Evaluation of Immunofluorescent and Direct Agglutination Methods for Detection of Specific Toxoplasma Antibodies

Abstract

Toxoplasma antibodies in human sera have been quantitatively assessed by indirect fluorescent antibody staining. The results obtained correlate well with those obtained by the dye test, by the direct-agglutination test, and by complement fixation. The fluorescent method is slower, but its specificity has been established by absorption studies and by lack of cross-reaction with sera from cases of trypanosomiasis, malaria, kala-azar, sarcosporidiosis, leptospirosis, syphilis, schistosomiasis, and filariasis. © 1964, British Medical Journal Publishing Group. All rights reserved.