Simulation of Multi-Frequency Induced Currents in Biophysical Models and Agar Phantoms of Breast Cancer

Abstract

Breast cancer is the most frequent malignant neoplasm and the leading cause of cancer death in women in the world. Early detection techniques have been proposed on the basis of bioelectrical measurements. The aim of this study was to evaluate analytically and experimentally the inductive phase shift as a function of multi-frequency induced currents in breast cancer conditions. Virtual simulation by biophysical models and experimental measurements by magnetic induction in agar phantoms were developed to estimate the inductive phase shift as a function of the bulk electrical properties in typical breast volumes with tumors in specific positions. The analytical and experimental results are qualitatively consistent and provide evidence that the inductive phase shift has a potential clinical value to detect cancerous tumors toward inside a typical volume of breast tissue.