Studies on the Constituents of Medicinal Plants. XX. The Constituent of the Vines of Menispermum dauricum DC.

Abstract

Menisdaurin, a new nitrile glucoside was isolated from the vines of Menispermum dauricum DC (Menispermaceae). The structure I, (Z)-6(S)-(β-D-glucopyranosyloxy)-4(R)-hydroxy-2-cyclohexene-Δ1,α-acetonitrile has tentatively proposed for menisdaurin and the structure III, (Z)-4(R)-6(S)-dihydroxy-2-cyclohexene--Δ1,α-acetic acid Ύ-lactone for menisdaurilide, the hydrolysis product of menisdaurin, on the basis of the chemical and spectral evidences. © 1978, The Pharmaceutical Society of Japan. All rights reserved.