Research progress on the synthesis of brazilin-type natural products

Abstract

Brazilin-type natural products were isolated from the heartwood of Caesalpinia sappan, a famous traditional Chinese medicine. These compounds have stimulated a great deal of interest on synthetic chemists due to their structural novelty and promising biological activities. Up to now, many methods towards the synthesis of these natural products have been developed. Progress on the synthesis of Brazilin-type natural products are reviewed in this paper.