Few years after HTLV-1 identification and isolation in humans, STLV-1, its simian counterpart, was discovered. It then became clear that STLV-1 is present almost in all simian species. Subsequent molecular epidemiology studies demonstrated that, apart from HTLV-1 subtype A, all human subtypes have a simian homolog. As HTLV-1, STLV-1 is the etiological agent of ATL, while no case of TSP/HAM has been described. Given its similarities with HTLV-1, STLV-1 represents a unique tool used for performing clinical studies, vaccine studies as well as basic science.
CITATION STYLE
Jégado, B., Kashanchi, F., Dutartre, H., & Mahieux, R. (2019, December 16). STLV-1 as a model for studying HTLV-1 infection. Retrovirology. BioMed Central Ltd. https://doi.org/10.1186/s12977-019-0503-0
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