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Iodine/aqueous NH4OAc: An improved reaction system for direct oxidative conversion of aldehydes and alcohols into nitriles

Journal of Chemical Research (2008) (1) 18-19
DOI: 10.3184/030823408X283711
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Abstract

A convenient method for direct oxidative conversion of aldehydes and alcohols into nitriles has been developed by using the inexpensive and environmentally friendly reagent I2/aqueous NH4OAc. The aqueous NH4OAc as a non-toxic cyanide source is more eco-friendly than aqueous ammonia, because gaseous ammonia evaporates easily from aqueous ammonia but not from aqueous NH4OAc.

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Ren, Y. M., Zhu, Y. Z., & Cai, C. (2008). Iodine/aqueous NH4OAc: An improved reaction system for direct oxidative conversion of aldehydes and alcohols into nitriles. Journal of Chemical Research, (1), 18–19. https://doi.org/10.3184/030823408X283711

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