Efficacy of Tetracycline and Niacinamide for the Treatment of Superficial Pemphigus (Pemphigus Foliaceus, Pemphigus Erythematosus) in 34 Dogs (1995-2010)

Abstract

Thirty-four dogs with superficial pemphigus (pemphigus foliaceus, pemphigus erythematosus) were treated with tetracycline and niacinamide (TCN). Follow-up information was available for 29 dogs and 62% of those responded satisfactorily to TCN. Success or failure of TCN treatment was not associated with patient sex, duration of disease prior to treatment, previous systemic glucocorticoid therapy, the presence or absence of pruritus, duration of TCN administration, TCN dosage, ability to reduce the frequency of administration of TCN, or distribution of skin lesions.