Synthesis and properties of acridone-labeled base-discriminating fluorescent (BDF) nucleosides.

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Abstract

We have developed novel acridone-labelled BDF probe which showed its potential in recognizing opposite matched base from its target sequence via enhancement of fiuorescence intensity. This probe emit at a longer wavelength than previously reported pyrene-labelled BDF probe and thus can be used in DNA chip.

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Saito, Y., Hanawa, K., Bag, S. S., Motegi, K., & Saito, I. (2006). Synthesis and properties of acridone-labeled base-discriminating fluorescent (BDF) nucleosides. Nucleic Acids Symposium Series (2004), (50), 181–182. https://doi.org/10.1093/nass/nrl090

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