Incidence and Prognosis of Acute Kidney Injury with COVID-19 in Hospitalized Egyptian Patients

Abstract

Background: The recent worldwide pandemic of COVID-19 has been a serious, multidimensional problem that has left a detrimental worldwide impact on individuals of all ages and several organ systems. The typical manifestation of kidney involvement is acute kidney injury (AKI); however, there is a lack of consensus data regarding AKI epidemiology in COVID-19. Objective: The aim of the current work was to study the incidence and prognosis of acute kidney injury among patients hospitalized with COVID-19. Subjects and methods: This retrospective, observational cohort study was conducted on 163 COVID19 patients diagnosed by RT-PCR and carried in Inpatient and ICU of Geriatric Isolation Hospital, Ain Shams University hospitals for COVID19. Results: As regard predictors for AKI; each of presence of chronic kidney disease, mechanical ventilation, CRP > 74, and TLC >13 had high predictive value for occurrence of AKI among hospitalized COVID 19 patients. Conclusion: It could be concluded that AKI in COVID-19 patients is associated with a high mortality rate in ICU-COVID-19 patients. Our findings suggest that COVID-19 patients, particularly ICU COVID-19 patients, should be closely monitored for the development of AKI. Early identification of AKI, as well as prompt intervention, can improve COVID-19 patient outcomes.