Activator protein-1 transcription factors in pathological cancers

Abstract

Activator protein-1 transcription factors play a critical role in the development of many cancers. Although many studies indicated the role of transcription factors driving the progression of cancer, there is still a knowledge gap in the process of better understanding the molecular mechanisms controlled by AP-1 transcription factors during cancer advancement. In conclusion, we have evaluated the role of transcription factors which provides new insights into mechanisms of regulation of colorectal cancer by AP-1 family transcription factors.