Differential immunodetection of toxin B from highly virulent clostridium difficile BI/NAP-1/027

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Abstract

We developed a simple immunoassay capable of differentially detecting toxin B from highly virulent strains of Clostridium difficile (BI/NAP-1/027) in stool. This assay can simultaneously confirm the presence of in vivo toxin production and provide strainrelated information relevant to infection control epidemiology and disease prognosis.

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Pollock, N. R., Song, L., Zhao, M., Duffy, D. C., Chen, X., Sambol, S. P., … Kelly, C. P. (2015). Differential immunodetection of toxin B from highly virulent clostridium difficile BI/NAP-1/027. Journal of Clinical Microbiology, 53(5), 1705–1708. https://doi.org/10.1128/JCM.03419-14

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