Synthesis, Water Solubility, and Inclusion Properties of Thioureido β-Cyclodextrins

  • Ortiz Mellet C
  • Garcia Fernandez J
  • Maciejewski S
  • et al.
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Abstract

A symposium on the prepn. of deoxythioureidocyclomaltoheptaoses. A marked increase in the water soly. of these adducts as compared to the native b-CD is obsd., even for derivs. incorporating hydrophobic substituents. Saccharide as well as glycopeptide antennae have been also efficiently appended to the b-CD core through thiourea spacers. By using these thioureido-b-CD conjugates, the water soly. of the anticancer agent taxotere was raised up to 4.7 g L-1. [on SciFinder (R)]

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APA

Ortiz Mellet, C., Garcia Fernandez, J. M., Maciejewski, S., & Defaye, J. (1996). Synthesis, Water Solubility, and Inclusion Properties of Thioureido β-Cyclodextrins. In Proceedings of the Eighth International Symposium on Cyclodextrins (pp. 141–144). Springer Netherlands. https://doi.org/10.1007/978-94-011-5448-2_30

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