Immobilization of la on THH-CO2H@Fe3O4nanocomposite for the synthesis of one-pot multicomponent reactions

Abstract

The current research represents a facile and competent methodology in the development of a novel magnetic nanocatalyst. This composite was synthesized by immobilizing La on Fe3O4 nanoparticles pre-functionalized with tetrahydroharman-3-carboxylic acid ligand. The prepared nanomaterial was analyzed with FT-IR, SEM, EDX, XRD, and TGA techniques. The material was catalytically investigated towards the synthesis of 5-substituted 1H-tetrazoles,1-substituted 1H-tetrazoles and tetrazolopyrimidine derivatives following different multicomponent pathways. The reactions were highly efficient affording high yields. The catalyst was retrieved magnetically and recyled in six consecutive runs without much reduction in activity.