Chemosensors Development for Selective Detection of Biologically Relevant Small Molecules and Biomolecules

Abstract

The detection of different biologically relevant species like cations, anions, reactive species and biomolecules is an important challenge. Various chemosensors have been developed for the selective detection of cations like metal ions which play a vital role in our daily physiological life and some toxic metal ions, which cause serious health and environmental problems. Simultaneously, the detection of anions and reactive species is crucial as they also play a vital role in a range of physiological and pathological processes. On the other hand, the study of interactions of nucleic acids with various ligands is an active research area as the binding ligands represent paradigms for drug design in anticancer therapy. In this chapter, various fluorescent chemosensors are reported for the detection of biologically and/or environmentally important species as well as the basic principles involved in the design of the chemosensors for specific analytes associated with problems as well as challenges.