Fulminating Fat Embolism Syndrome Caused by Paradoxical Embolism through a Patent Foramen Ovale

  • Pell A
  • Hughes D
  • Keating J
  • et al.
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Abstract

The post-traumatic fat embolism syndrome is a multisystem disorder characterized by pulmonary and neurologic dysfunction, pyrexia, and a petechial rash1–4. More than a century after the first descriptions of the fat embolism syndrome, the cause of fat emboli and the pathogenesis of the systemic manifestations of this disorder remain incompletely understood. We describe a patient undergoing treatment of a femoral fracture in whom massive fat embolism was demonstrated by transesophageal echocardiography. Acute cor pulmonale developed, precipitating paradoxical fat embolism across a patent foramen ovale, with the subsequent development of the fat embolism syndrome. Embolism of fat across a… © 1993, Massachusetts Medical Society. All rights reserved.

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Pell, A. C. H., Hughes, D., Keating, J., Christie, J., Busuttil, A., & Sutherland, G. R. (1993). Fulminating Fat Embolism Syndrome Caused by Paradoxical Embolism through a Patent Foramen Ovale. New England Journal of Medicine, 329(13), 926–929. https://doi.org/10.1056/nejm199309233291305

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