Increase in invasive group A streptococcal (Streptococcus pyogenes) infections (iGAS) in young children in the Netherlands, 2022

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Abstract

In 2022, a sevenfold increase in the number of notifiable invasive Streptococcus pyogenes (iGAS) infections among children aged 0-5 years was observed in the Netherlands compared with pre-COVID-19 pandemic years. Of 42 cases in this age group, seven had preceding or coinciding varicella zoster infections, nine were fatal. This increase is not attributable to a specific emm type. Vigilance for clinical deterioration as iGAS sign is warranted in young children, especially those with varicella zoster infection.

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De Gier, B., Marchal, N., De Beer-Schuurman, I., Te Wierik, M., Hooiveld, M., De Melker, H. E., … Vlaminckx, B. J. M. (2023). Increase in invasive group A streptococcal (Streptococcus pyogenes) infections (iGAS) in young children in the Netherlands, 2022. Eurosurveillance, 28(1). https://doi.org/10.2807/1560-7917.ES.2023.28.1.2200941

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