Nd3+ sensitized up/down converting dual-mode nanomaterials for efficient in-vitro and in-vivo bioimaging excited at 800 nm

200Citations
Citations of this article
127Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Core/shell1/shell2/shell3 structured NaGdF4:Nd/NaYF4/NaGdF4:Nd, Yb, Er/NaYF4 nanocrystals were well designed and synthesized, each of the parts assume respective role and work together to achieve dual-mode upconverting (UC) and downconverting (DC) luminescence upon the low heat effect 800-nm excitation. Nd31, Yb31, Er31 tri-doped NaGdF4:Nd, Yb, Er UC layer [NIR (800 nm)-to-Visible (540 nm)] with a constitutional efficient 800 nm excitable property were achieved for the in-vitrobioimaging with low auto-fluorescence and photo-damage effects. Moreover, typical NIR (800 nm)-to-NIR (860-895 nm) DC luminescence of Nd3+ has also been realized with this designed nanostructure. Due to the low heat effect, high penetration depth of the excitation and the high efficiency of the DC luminescence, the in-vivohigh contrast DC imaging of a whole body nude mouse was achieved. We believe that such dual-mode luminescence NCs will open the door to engineering the excitation and emission wavelengths of NCs and will provide a new tool for a wide variety of applications in the fields of bioanalysis and biomedical.

Cite

CITATION STYLE

APA

Li, X., Wang, R., Zhang, F., Zhou, L., Shen, D., Yao, C., & Zhao, D. (2013). Nd3+ sensitized up/down converting dual-mode nanomaterials for efficient in-vitro and in-vivo bioimaging excited at 800 nm. Scientific Reports, 3. https://doi.org/10.1038/srep03536

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free