Sensitive detection of SARS-CoV-2-Specific antibodies in dried blood spot samples

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Abstract

Dried blood spot (DBS) samples can be used for the detection of severe acute respiratory syndrome coronavirus 2 spike antibodies. DBS sampling is comparable to matched serum samples with a relative 98.1% sensitivity and 100% specificity. Thus, DBS sampling offers an alternative for population-wide serologic testing in the coronavirus pandemic.

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Morley, G. L., Taylor, S., Jossi, S., Perez-Toledo, M., Faustini, S. E., Marcial-Juarez, E., … O’Shea, M. K. (2020). Sensitive detection of SARS-CoV-2-Specific antibodies in dried blood spot samples. Emerging Infectious Diseases, 26(12), 2970–2973. https://doi.org/10.3201/EID2612.203309

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