Influenza is the leading cause of death from an infectious cause. Because of its clinical importance, many investigators use animal models to understand the biologic mechanisms of influenza A virus replication, the immune response to the virus, and the efficacy of novel therapies. This review will focus on the biosafety, biosecurity, and ethical concerns that must be considered in pursuing influenza research, in addition to focusing on the two animal models – mice and ferrets – most frequently used by researchers as models of human influenza infection.
CITATION STYLE
Radigan, K. A., Misharin, A. V., Chi, M., & Budinger, G. R. S. (2015, August 31). Modeling human influenza infection in the laboratory. Infection and Drug Resistance. Dove Medical Press Ltd. https://doi.org/10.2147/IDR.S58551
Mendeley helps you to discover research relevant for your work.