'Cutis tricolor': Congenital hyper- and hypopigmented macules associated with a sporadic multisystem birth defect: An unusual example of twin spotting?

Abstract

An uncommon coexistence of circumscribed hyperpigmentation and hypopigmentation, in close proximity to each other, is described in a 17 year old patient with various other congenital defects, such as dysmorphic facial appearance, severe kyphoscoliosis, delayed motor development, epileptic seizures, and mental retardation. We suggest the combination of hyper- and hypopigmented cutaneous lesions is an example of allelic twin spotting. Because the skin of this patient showed three different degrees of pigmentation, the term 'cutis tricolor' is proposed.