Eight antimicrobial compounds were examined to evaluate their therapeutic effects against experimentally or naturally induced vibriosis of the Pacific oyster Crassostrea gigas. In experimental infections with a strain of Vibrio splendidus biovar II, a causative agent of bacillary necrosis of cultured triploid oyster larvae, chloramphenicol (CP) exhibited complete protection against challenges at 105 or 106 CFU/mL, and erythromycin (EM), novobiocin (NB), gentamicin and streptomycin (SM) were effective to reduce the mortality, but nalidixic acid or oxytetracycline was not. CP and EM were also highly effective against experimental infections with other six strains of Vibrio species (V. splendidus biovar II, V. pelagius I, V. campbellii, and V. tubiashii) which had been isolated from oyster larvae or the rearing water, but NB and SM were less effective. On the other hand, not only CP and EM but also NB and SM exhibited higher protection against the natural infection.
CITATION STYLE
Matsubara, D., Tanaka, M., Soumyou, Y., Hirakawa, K., Doi, R., & Nakai, T. (2002). Therapeutic effects of antimicrobial compounds against bacillary necrosis of larval pacific oyster. Fish Pathology, 37(4), 183–188. https://doi.org/10.3147/jsfp.37.183
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