Abstract
A Michael addition/iminium ion cyclization cascade of enones with tryptamine-derived ureas under BINOL phosphoric acid (BPA) catalysis is reported. The cascade reaction tolerates a wide variety of easily synthesized tryptamine-derived ureas, including those bearing substituents on the distal nitrogen atom of the urea moiety, affording polyheterocyclic products in good yields and good to excellent enantioselectivities. © 2013 American Chemical Society.
Cite
CITATION STYLE
Aillaud, I., Barber, D. M., Thompson, A. L., & Dixon, D. J. (2013). Enantioselective Michael addition/iminium ion cyclization cascades of tryptamine-derived ureas. Organic Letters, 15(12), 2946–2949. https://doi.org/10.1021/ol401039h
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
