Analgesic Effect of Perioperative Escitalopram in High Pain Catastrophizing Patients after Total Knee Arthroplasty

  • Lunn T
  • Frokjaer V
  • Hansen T
  • et al.
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Abstract

In 120 patients with high pain catastrophizing scores before total knee arthroplasty, 1 week treatment with the serotonin selective reuptake inhibitor escitalopram did not differ from placebo in pain on ambulation 24 h after surgery.

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Lunn, T. H., Frokjaer, V. G., Hansen, T. B., Kristensen, P. W., Lind, T., & Kehlet, H. (2015). Analgesic Effect of Perioperative Escitalopram in High Pain Catastrophizing Patients after Total Knee Arthroplasty. Anesthesiology, 122(4), 884–894. https://doi.org/10.1097/aln.0000000000000597

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