Other tests in glaucoma: Genetic testing

Abstract

One of the goals of human genetic research is to develop novel diagnostic and screening tests based on the identification of the genes responsible for the disease. Over the past decade ten genes have been shown to contribute to various forms of human -glaucoma including: primary open angle glaucoma (MYOC, OPTN, WDR36, OPA1), glaucoma associated with Axenfeld-Rieger syndrome and other anterior segment dysgenesis disorders (FOXC1, PITX2, PAX6, LMX1B), congenital glaucoma (CYP1B1), and most recently pseudoexfoliation glaucoma (LOXL1) [1-5]. © 2010 Springer-Verlag Berlin Heidelberg.