Characterization and Utilization of Starches Extracted from Florencia and Waxy Maize Hybrids for Tablet Formulation: Compaction Behaviour and Tablet Properties

Abstract

The aim of this work is to analyze theparticle characteristics, such as shape, roundness and size, of starchesextracted from Florencia and waxy maize hybrids. The micromeritics andstructural properties of the samples were examined. The evaluation of flowproperties, densification and compression behaviour of the powders was carriedout. Physical parameters and swelling characteristics of tablets containingFlorencia and waxy maize starch were also studied. Starch samples were comparedwith respect to their applicability as excipients in tablet formulation. Thesamples exhibited identical structure and similar particle characteristics.Maize starch extracted from the Florencia dent hybrid showed better flowabilityand compressibility in tableting experiments, which resulted in bettermechanical tablet properties. With regard to utilization as a disintegrant,Florencia starch indicated rapid and intensive swelling and proved to act moreeffectively in the swelling process than waxy maize starch.