Further observations on the diurnal variation in oral glucose tolerance

Abstract

Diurnal variation in oral glucose tolerance was studied in 122 male volunteers aged 40 years and over who participated in a screening health examination. In those with screening blood sugar levels exceeding 110 mg./100 ml. the degree of diurnal variation was least in those with the highest morning glycaemia; the latter also tended to have lower afternoon fasting blood sugar levels. In a group of 40 control subjects, afternoon glucose tolerance tests yielded significantly higher post-glucose blood sugar levels. The degree of diurnal variation was significantly and inversely related to the degree of obesity. © 1970, British Medical Journal Publishing Group. All rights reserved.