Co(Ii) complex of quercetin–spectral, anti‐/pro‐oxidant and cytotoxic activity in hacat cell lines

Abstract

In this study a cobalt(II) complex of quercetin was synthetized in the solid state with the general formula Co(C15H9O7)2∙2H2O. The FT‐IR, elemental analysis, and UV/Vis methods were used to study the composition of the complex in a solid state and in a water solution. The anti‐/pro-oxidant activity of quercetin and the Co(II) complex was studied by means of spectrophotometric DPPH (2,2‐diphenyl‐1‐picrylhydrazyl), FRAP (ferric reducing antioxidant activity) and Trolox oxidation assays. The cytotoxicity of quercetin and Co(II)‐quercetin complex in HaCat cell lines was then established.