To fully examine the functionality of a regulatory T cell (Treg) population, one needs to assess their ability to suppress in a variety of in vivo models. We describe five in vivo models that examine the suppressive capacity of Tregs upon different target cell types. The advantages and disadvantages of each model including resources, time, and technical expertise required to execute each model are also described.
CITATION STYLE
Workman, C. J., Collison, L. W., Bettini, M., Pillai, M. R., Rehg, J. E., & Vignali, D. A. A. (2011). In Vivo Treg Suppression Assays. In Methods in Molecular Biology (Vol. 707, pp. 119–156). Humana Press Inc. https://doi.org/10.1007/978-1-61737-979-6_9
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