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A linear polyethylenimine mediated siRNA-based therapy targeting human epidermal growth factor receptor in SPC-A1 xenograft mice

  • Zhang P
  • Xu N
  • Zhou L
  • et al.
Translational Respiratory Medicine (2013) 1(1)
DOI: 10.1186/2213-0802-1-2
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Abstract

Linear polyethylenimine (LPEI) is considered as a desirable gene in vivo delivery system, but whether it could deliver the specific siRNA targeted EGFR to the tumor site to inhibit the growth of NSCLC xenograft in nude mice still needs to be examined.

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Zhang, P., Xu, N., Zhou, L., Xu, X., Wang, Y., Li, K., … Bai, C. (2013). A linear polyethylenimine mediated siRNA-based therapy targeting human epidermal growth factor receptor in SPC-A1 xenograft mice. Translational Respiratory Medicine, 1(1). https://doi.org/10.1186/2213-0802-1-2

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