Quercetin and Bornyl Acetate regulate T-lymphocyte subsets and INF-γ/IL-4 ratio in utero in pregnant mice

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Abstract

The objective of this study is to investigate the antiabortive effects of Quercetin and Bornvl Acetate and their immunological modulation at maternal-fetal interface. Lipopolysaccharide (LPS) was injected via tail vein to induce abortion in mice which received Quercetin and Bornyl Acetate at days 4-7 of gestation. Uterine CD4+/CD8+ T lymphocytes and INF-γ/IL-4 of each group (n=10) were detected by immunohistochemistry and enzyme-linked immunosorbent assay, respectively. The ratio of CD4+/CD8+ increased significantly (P

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Zhong, X., Wang, X., Ma, A., Shi, W., Geng, M., & Zhao, Y. (2011). Quercetin and Bornyl Acetate regulate T-lymphocyte subsets and INF-γ/IL-4 ratio in utero in pregnant mice. Evidence-Based Complementary and Alternative Medicine, 2011. https://doi.org/10.1155/2011/745262

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