Abstract
A highly efficient procedure for the synthesis of 4-alkyl(aryl)-6-aryl-3- cyano-2(1H)-pyridinones and their 2-imino isosteres via a one-pot multicomponent reaction of 3,4-dimethoxyacetophenone, malonitrile or ethyl cyanoacetate, an aldehyde and ammonium acetate in the presence of K2CO3 is achieved in good yields. © 2010 Chemical Society of Ethiopia.
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Beheshtia, Y. S., Khorshidi, M., Heravi, M. M., & Baghernejad, B. (2010). A catalytic method for the synthesis OF 4-alkyl(aryl)-6-Aryl-3-Cyano-2(1H)- pyridinones and their 2-Imino isosteres as nonsteroidal cardiotonic agents. Bulletin of the Chemical Society of Ethiopia, 24(3), 433–438. https://doi.org/10.4314/bcse.v24i3.60691
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