A matter of time: study of circadian clocks and their role in inflammation

  • Carter S
  • Durrington H
  • Gibbs J
  • et al.
57Citations
Citations of this article
133Readers
Mendeley users who have this article in their library.

Abstract

Circadian rhythms regulate changes in physiology, allowing organisms to respond to predictable environmental demands varying over a 24 h period. A growing body of evidence supports a key role for the circadian clock in the regulation of immune functions and inflammatory responses, which influence the understanding of infections and inflammatory diseases and their treatment. A variety of experimental methods have been used to assess the complex bidirectional crosstalk between the circadian clock and inflammation. In this review, we summarize the organization of the molecular clock, experimental methods used to study circadian rhythms, and both the inflammatory and immune consequences of circadian disturbance.

Cite

CITATION STYLE

APA

Carter, S. J., Durrington, H. J., Gibbs, J. E., Blaikley, J., Loudon, A. S., Ray, D. W., & Sabroe, I. (2016). A matter of time: study of circadian clocks and their role in inflammation. Journal of Leukocyte Biology, 99(4), 549–560. https://doi.org/10.1189/jlb.3ru1015-451r

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free