There are many brain proteins that participate in the early growth and development of the mammalian central nervous system. Reelin is a glycoprotein that helps guide brain development in an orderly fashion. Changes in the level of this protein or its receptors or downstream proteins may cause abnormal corticogenesis and alter synaptic plasticity. These changes have also been observed in a number of neuropsychiatric disorders. We will discuss more about this protein and its possible involvement in various neuropsychiatric disorders.
CITATION STYLE
Fatemi, S. H., Reutiman, T. J., & Folsom, T. D. (2008). The role of Reelin in etiology and treatment of psychiatric disorders. In Reelin Glycoprotein: Structure, Biology and Roles in Health and Disease (pp. 317–339). Springer New York. https://doi.org/10.1007/978-0-387-76761-1_22
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