Etoposide (VP 16-213) and teniposide (VM 26) are semisynthetic epipodophyllotoxin derivatives active against a variety of tumours. The clinical efficacy has led to an increasing interest in these compounds. This review presents information on the mechanism of action, biochemical pharmacology, bioanalysis, metabolism and pharmacokinetics of etoposide and teniposide. © 1988 Royal Dutch Association for Advancement of Pharmacy.
CITATION STYLE
Holthuis, J. J. M. (1988, June). Etoposide and teniposide - Bioanalysis, metabolism and clinical pharmacokinetics. Pharmaceutisch Weekblad Scientific Edition. Kluwer Academic Publishers. https://doi.org/10.1007/BF01959294
Mendeley helps you to discover research relevant for your work.