Intracranial Response to Anti-Programmed Death 1 Therapy in a Patient with Metastatic Non-Small Cell Lung Cancer with Leptomeningeal Carcinomatosis

  • Kamath S
  • Kumthekar P
  • Kruser T
  • et al.
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Abstract

Central nervous system metastasis in non-small cell lung cancer remains a therapeutic challenge and confers a poor prognosis. Here we describe a patient with lung adenocarcinoma, parenchymal brain metastases, and leptomeningeal carcinomatosis who demonstrated a sustained response to programmed death 1 inhibition combined with stereotactic radiosurgery.

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Kamath, S. D., Kumthekar, P. U., Kruser, T. J., & Mohindra, N. A. (2018). Intracranial Response to Anti-Programmed Death 1 Therapy in a Patient with Metastatic Non-Small Cell Lung Cancer with Leptomeningeal Carcinomatosis. The Oncologist, 23(12), e159–e161. https://doi.org/10.1634/theoncologist.2018-0022

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