Intraspinal extradural gout tophus in the lumbar vertebral canal Case reports

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Abstract

Rationale: Intraspinal gout tophus in the lumbar vertebral canal associated with gouty arthritis is rare. We present 2 cases with the first manifestations of a sequestrated intervertebral disc and an extradural tumor, and histopathologically proven to be gouty deposits in the lumbar vertebral canal. Patient concerns: The 2 patients presented with typical radiculopathy symptoms and a positive straight leg raise. In 1 case, there was weakness of the left toe extensors, with a positive left femoral nerve traction test. Additionally, the left patellar tendon reflex was weak. In the other patient who was unable to walk, there was a sensory deficit in the saddle distribution. Diagnosis: Histopathological examination of the specimens taken from the operation confirmed the presence of gouty deposits. Interventions: Posterior decompression was performed in these 2 cases, and chalky-white materials were identified in the lumbar vertebral canal. Outcomes: No evidence of neoplasm, infection, or synovial cyst was found. Lessons: Definitive diagnosis of intraspinal extradural gout tophus, mimicking a sequestrated intervertebral disc or an extradural tumor, may be difficult. The initial suspicion of intraspinal gouty deposits, based on the diagnostic/management algorithm, may effectively avoid incorrect diagnosis via a less invasive procedure than explorative laminectomy.

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Wu, Z., Liu, C., Dai, K., & Zheng, C. (2022). Intraspinal extradural gout tophus in the lumbar vertebral canal Case reports. Medicine (United States), 101(1), E28418. https://doi.org/10.1097/MD.0000000000028418

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