Stem cell therapy and orthopedics

Abstract

Stem cells obtained from various sources in the body and during different stages of development form the basis of cellular therapy and are often studied in the field of orthopedic regenerative medicine. Parameters such as potential, source, route of administration, and desired dose of stem cells to be used should be selected according to the type of regeneration, and research and application should be conducted with this in mind. This chapter details the general characteristics of stem cells, sources of stem cells, and the advantages and disadvantages of the various sources of stem cells. Detailed specifications of adult stem cells in the group of mesenchymal stem cells, which have more advantages in the field of orthopedics than other stem cells, are provided. Briefly, induced pluripotent stem cells and tissue engineering studies are discussed and examples of orthopedic studies with stem cells are provided.