Polymeric nanocapsules for topical delivery

Abstract

Polymeric nanocapsules represent an interesting carrier system for cutaneous applications. The possibilities of modulating skin penetration/permeation by altering the design of the formulation and the range of applicability are the main subjects under study. With this in mind, this chapter will address methods of nanocapsule preparation and the influence of the polymeric wall, the surface functionalization, and the vehicle on the skin penetration/permeation profile of active substances loaded in polymeric nanocapsules. Additionally, therapeutic and cosmetic applications of nanocapsules will also be discussed.