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Synthesis of 3,4-Dihydropyrimidin-2(1H)-Ones and Their Corresponding 2(1H)Thiones Using Trichloroacetic Acid as a Catalyst under Solvent-Free Conditions

  • Karimi-Jaberi Z
  • Moaddeli M
ISRN Organic Chemistry (2012) 2012 1-4
DOI: 10.5402/2012/474626
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Abstract

Trichloroacetic acid was found to be a convenient catalyst for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones and their corresponding 2(1H)-thiones through a one-pot three-component reaction of aldehydes, alkyl acetoacetate, and urea or thiourea at 70°C under solvent-free conditions.

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APA

Karimi-Jaberi, Z., & Moaddeli, M. S. (2012). Synthesis of 3,4-Dihydropyrimidin-2(1H)-Ones and Their Corresponding 2(1H)Thiones Using Trichloroacetic Acid as a Catalyst under Solvent-Free Conditions. ISRN Organic Chemistry, 2012, 1–4. https://doi.org/10.5402/2012/474626

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