Study on cellulose/chondroitin sulfate hydrogel used in drug release systems

Abstract

The aim of this study was to combine the properties of cellulose and chondroitin sulfate in mixed hydrogels in order to obtain new materials for medical and pharmaceutical applications as drug delivery systems. Different swelling profiles and active drug release rates were observed for the proposed formulation compared with pure cellulose hydrogels. Along with this aim, hemotoxicity and subcutaneous implantation experiments had been performed showing a good biocompatibility of the studied hydrogels.