Microbiological and Antimicrobial Profile of Urinary Tract Infection in Children from A Teaching Hospital in South India

Abstract

© 2017 by Pediatric Infectious Diseases Society. Objective: Urinary tract infections are an important healthcare issue and are responsible for nearly 3% of all infections among the pediatric population. There are increasing reports on rising antibiotic resistance and these reports stress the continual surveillance of antimicrobial efficacy, particularly in countries with wide antibiotic abuse. This retrospective study aims to analyze the resistance of bacterial isolates to commonly used antibiotics in pediatric populations. Material and Methods: In this study, records of all urine isolates and their antibiotic susceptibility profile from pediatric patients (1 month to 15 years) visiting a teaching hospital in south India in between June 2012 and December 2012 were evaluated. Results: Of 342 samples tested, 62 (18.1%) showed significant growth, and 42(67.8%) were from children under 5 years of age, with male predominate. Escherichia coli (48.4%) the most prevalent urinary pathogen, resistant to cephalosporin (87.5%) and fluroquinolones (81.7%) and lowest resistance to nitrofurantoin (30%) and aminoglycoside (38.3%), Conclusion: The uropathogens causing UTI in the pediatric population are highly resistant to most of the antibiotics recommended for empiric use in the therapy of UTI. Development of regional surveillance programs is necessary for implementation of national UTI guidelines.